6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
tert-butyl 6-amino-1H-indazole-1-carboxylate
CAS: 219503-81-8
Molecular Formula: C12H15N3O2
6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Names and Identifiers
| Name | tert-butyl 6-amino-1H-indazole-1-carboxylate |
| Synonyms | LogP 1-BOC-6-AMINO-INDAZOLE 6-Amino-1H-indazole, N1-BOC 6-Amino-1H-indazole, N1-BOC protected 6-AMINO-1-N-TERT-BUTOXYCARBONYL-1H-INDAZOLE tert-butyl 6-amino-1H-indazole-1-carboxylate 6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 6-AMINO-1H-INDAZOLE-1-CARBOXYLIC ACID, 1,1 DIMETHYL ETHYL ESTER 1H-Indazole-1-carboxylic acid, 6-aMino-, 1,1-diMethylethyl ester |
| CAS | 219503-81-8 |
| InChI | InChI=1/C12H15N3O2/c1-12(2,3)17-11(16)15-10-6-9(13)5-4-8(10)7-14-15/h4-7H,13H2,1-3H3 |
6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Physico-chemical Properties
| Molecular Formula | C12H15N3O2 |
| Molar Mass | 233.27 |
| Density | 1.24±0.1 g/cm3(Predicted) |
| Melting Point | 171-172℃ |
| Boling Point | 395.3±34.0 °C(Predicted) |
| Flash Point | 192.8°C |
| Water Solubility | Slightlysoluble in water. |
| Vapor Presure | 1.86E-06mmHg at 25°C |
| Appearance | Powder |
| pKa | 2.52±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.596 |
6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Introduction
tert-butyl is an organic compound with the chemical formula C12H16N2O2. It is a white solid with a low melting and boiling point. tert-butyl is a heterocyclic compound with nitrogen, with structural units of indazole and formate. It is soluble in many organic solvents.
tert-butyl has important applications in the field of pharmaceutical chemistry. It is a potential indazole prodrug and can be used to synthesize a series of Indazole derivatives. These derivatives have a wide range of applications in drug research, and may exhibit anti-tumor, anti-inflammatory, and antibacterial activities.
The method of preparing tert-butyl usually involves the modification of indazole compounds. A common synthetic method is to prepare tert-butyl by reacting 6-aminoindazole with an acid chloride N-Boc a protecting group.
For safety information, tert-butyl are generally stable under normal operating conditions and are not prone to decomposition or combustion. However, it may have an irritating effect on the skin, eyes and respiratory tract. Therefore, appropriate protective measures such as wearing protective gloves, goggles and masks are required during handling and use. In addition, it should be stored in a dry, cool place, kept separate from oxidants and strong acids. If necessary, operate in a well-ventilated environment. When discomfort or accidental contact occurs, seek medical attention or medical attention immediately.
tert-butyl has important applications in the field of pharmaceutical chemistry. It is a potential indazole prodrug and can be used to synthesize a series of Indazole derivatives. These derivatives have a wide range of applications in drug research, and may exhibit anti-tumor, anti-inflammatory, and antibacterial activities.
The method of preparing tert-butyl usually involves the modification of indazole compounds. A common synthetic method is to prepare tert-butyl by reacting 6-aminoindazole with an acid chloride N-Boc a protecting group.
For safety information, tert-butyl are generally stable under normal operating conditions and are not prone to decomposition or combustion. However, it may have an irritating effect on the skin, eyes and respiratory tract. Therefore, appropriate protective measures such as wearing protective gloves, goggles and masks are required during handling and use. In addition, it should be stored in a dry, cool place, kept separate from oxidants and strong acids. If necessary, operate in a well-ventilated environment. When discomfort or accidental contact occurs, seek medical attention or medical attention immediately.
Last Update：2024-04-09 20:52:54
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Product Name: 1-Boc-6-Amino-Indazole Visit Supplier Webpage Request for quotationCAS: 219503-81-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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